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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4559af235b4aa2acb8c432823aef41ed4a6904e37761a122a552addf1e348d' 
  AND token = 'YLoPXAMRs78388JL9uLR8DNMSYrwk5vBLf0yOcrBuUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}