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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c9ff3ced54e5a0396f1e4a441e0065c2af327845b1bcfd8d9848327eed75f1d' 
  AND token = 'cy7qEfIHOfB5N4AGhetdJvN6bgeOXovgzpZNVhr6rF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}