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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a13dc23ebfa795aa470f733b769d1fbebe8c6b78d51c0216976de9194c343518' 
  AND token = '9hY3W6k+f/TpvxhKx1N+DCcyT1VpNlYpvp5g6re2Xdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}