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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b2b875f2b5532dc9f94a7c6ebb5e7366eb5afa04c2c3b0adda890b981fa8d81' 
  AND token = 'jto3aUuB1z2p08QTBKIb1cgrZSY2+Xik8vv/MQCB80k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}