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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a969dfc74cb60c02957a114cfbf94a888caedbf06f5f5e5a4cda6e764c9a95a' 
  AND token = 'P8U3zkMPDKEIZn9NekKnuSktHFP/oK6VKz+4ubpwxko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}