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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '808dccf30d461fe955548e907d89a7d03c61aaab8e54b9d095a205022a32cbed' 
  AND token = 'LQa3e5jRfWPsMaK3DTRMThkrsK0RfdFU5MFFY1EFxWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}