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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1025f4d114cf95b288e8f2ef71d8af5f5a127749292a936d8f56e99a499ea5d' 
  AND token = '6UfWHsAtGPm3+vbQzri2Sx5wmjy0M+uz6bRxk7s18YQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}