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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f99f1ac49451ccdcab8f4d02bf401b79a3cf9d0c1e82da49e2b78bd9b9f7f5c8' 
  AND token = 'mF8Q4yn7UCQE2wdXJgFtcPUYKLvS3AOcwXJrzuj08Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}