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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eb58b55c7d808ecc6cc128e782b120f6aacde289060b834316b432a3a8eb43c' 
  AND token = 'Sye3TTg5uVW38wUqvmoU7l8W3eCzIM+h1788VrUVxBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}