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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aa555ffdf05fa5ac30a6f1d14338504f1e3a6d2fcc934a60dab84e3e8ae38cc' 
  AND token = '8D7ucawvSAM1a5+/zm2zz7cqpTFvHCJvMolzo1DeBn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}