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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ae7f0e74398dfb3ac6cd59fed561bd2f249429a8c4a90494e65cf629aab51d8' 
  AND token = 'XJ+p0rJCi3UyMNWUQV8lGRZbyvIkfZrFtso3mKkjSj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}