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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad259b094f6442a9a40bb452e0c8dd35aaa9c98d748b9923c897e0279f7a7a4' 
  AND token = '4CwhVW79FS3O9nPFwRN3AE9fT3U8sT1dmOhWrreTFgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}