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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95ec5a23c2d4cf8b44b0b3466655faf1e6a57305e7128ca931ace96deb9cca7' 
  AND token = '+g9XloGtRMUNWKw6/77a0gEhKhv0u2ZCuMIX9rm8Ao0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}