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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e92a50802d53332d49eab9ee3e7cb04021f8c8571519d8a2064e821c8a976c' 
  AND token = 'Dm95Um1Rez6AhcSTf00PX7cM7GgFjtXjDb1WzhJHOPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}