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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c4959b535eab608efaef666cc6def4001c8a4cdbcc03b7d5c5f96c645c2794e' 
  AND token = 'OeqpmfheSsmBcppyaPwSEuDA2TJkKsqVVrvRk4dZ4nA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}