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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8146e524b7d3314700167de88a16bef50b337f9cc3024d13661be9f205096e6' 
  AND token = 'EDpaBoFtxfieOKjYLeOdWCMz9j6EeLr+dYGn0aEwrQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}