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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589e1ac6b0a28270eb3bf6e3bb2e335204989dd6551769e67c10d10408011b7f' 
  AND token = 'Ysk+E3owQZDX5Vw88LE2OYcL7vXvgOmorOComFN3Bwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}