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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11659f844099437588cb9f458989f7967ae1649f2860aa446f6789f5d43d1c52' 
  AND token = 'xnVGoO9EH5E14SOBHQ7D9vY3n8mSOMNlE+OSklkaOX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}