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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52157130e277a5469bfcfee0082f62213a38e85c8e75156e44813a54c3f5ddbc' 
  AND token = 'uNjOWw/ZnGFjUcuXnhPBcH1Bqg6CqbSHf8eTno8HqeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}