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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7421cbc2f623ae052675a4d0e12602a7ca2b96c5a3c242d392e2340692f3e361' 
  AND token = '3c4v23opjPRmlTYdwlLuPqlxA/EigHkFz2sKWksYagU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}