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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449db17e1f6e9e5f5f8459b12248a7cc165321ce9d1636c8e24407e1db49cab5' 
  AND token = 'qiHbOcikkrFGGYI+3MQqF59Q8mCiPmm18SKeFp7+8Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}