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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea864bbc3e6669339151fc73efa6d9895024e3f8bc2c94bf32f38d05f40b81af' 
  AND token = 'fpuzBeCv0ooGPTcmrZ5j2T1rOV1hl8nLLA4NDRnGgHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}