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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4def0f33080aa3661d25fa0e0b1893083de1ac8998f41576cbd8ea91df183264' 
  AND token = '5zpjOC8lgNzTnsOJl2x1TolZUH8ggfbzvOst1p0iLLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}