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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29eb37f894eb9dfc8f6f590e47133f1085ccfb821ae6b460f784596a12a2791b' 
  AND token = '5Ho9vinK6EEdReDPrksR/dpfkGEZRJ2NKcCqyrI1O9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}