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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6472a71e5eabb3f682a4d66ac5b2bc02db39b5ba4687d9046062d866fd396406' 
  AND token = 'sUZEp3X1U0pSvnj6IMweTYo9oko1tyCA0oycZuOqCjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}