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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa549f40945309b0745842bdb49cd2a38a1c652b2be4730c413888c50c893aac' 
  AND token = 'Iz8JiC/HUiE/D2wUj1ifckYP1eZ2ZwawM0TuV4bITrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}