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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd828447f89f4e46db8600bfc6fdb4c6cf8a9320db99b0b4f18f73f1fa26e53b8' 
  AND token = 'TZf7tAkTRKgyed8kOTgfBDNMdsuIVpHJmIxvTH9TDwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}