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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04c22017cb31f811ee9141fc72717abecc4d5dde3005604190e3da62683b4280' 
  AND token = 'TP+oW0IyrMeG2Ehi1Ul68s9gWIxk8CBRKV5zMyb8BFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}