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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46eb9a390727b99d6bd7aab505030cb5d7a6309af01cf83d2713c0feef97a6f5' 
  AND token = 'u4D1pl2zLzb1FreJ532Do8qMfYk7Z46Qks4XH4QOY80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}