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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed8a033337e4f03b4415a35bda0639215ae7a10515d23760d04de3010a0d2df2' 
  AND token = '4UNLV4vhcoiCFYKnufaGs8E/QGXVz3242QCx8QPpE44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}