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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ebb0fdb152a1d8f93d30e3ad249f303241248b187adc28776b6208b26d18c0a' 
  AND token = 'ZO9OKYS43sxr2tb6OkDLKJVyEnFVqPvclPpnwdjUmEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}