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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ea630a5a5c1a31c6d7a9c60ae95accc349e458dab271429a2eb77ff1d5e58c4' 
  AND token = 'Pu424WK4Y47R2vvZN8mB/hdV2+oIVKCdmzBarPhs7Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}