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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1244a59390c1974563f3574ae72dfb5b56f845cc9fe1d59a6cbb49a3b2bef42b' 
  AND token = 'qm7z7z3VtnZBk7p5NhaitBB9yOaNmyopa5KUVgMbmDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}