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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3f0e832b96ed65c8e9c8be1f788927f91001da2ab4aa67d9d171809eb4cf830' 
  AND token = 'a449HLkdEOdbBXoIboT1J4SJRbR1qxsYCCEGfFQXXu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}