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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37123081f8d6b32d69782f2215e696216dc435f5a9a37c3232a2f300492ac851' 
  AND token = 'LXBN+KM7ytK0fEdEVmzjzfkkW4vKa3FNFk7vjMSgMTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}