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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd95a6f1979dcd0e0b2af4ed57c1365c9a06f522ac9b52d0937ecbe758e29edd3' 
  AND token = 'cvwXk8FfvEIQFyL2S2794YcWk6nkRQPiyrrA+S9V3Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}