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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef73af63678d35145ce94a35a796e2e3545d693b3af12b497bb29ce21ce15c37' 
  AND token = '4cmzFIwhmkpG2fzY2RRLE2mVhxvKIs5vKKpV05IocDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}