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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf00c58e2a8399c7999bd95d5a0171312e9300ee84e112335eaab14cf76b6b33' 
  AND token = 'wHRrWOzOtxFeqF6TwNVtwT0Y6qAdprbmmbwI5qP9dVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}