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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd29f2a9ea12cf024d75156afe3b780533b5d440056ae05b353380dea77dabd79' 
  AND token = 'X3z1UiPbOYHoLx5jQ1/6/jNF2sFzS14Oz50GGNEGUeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}