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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c42ea868702c687d20c2015cae67b5d386597a083ebe4145c95a72a8759c3bc1' 
  AND token = 'USMecXIR7ZakLbU0j02i9BHzW9NISdJszrd3NXbTd2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}