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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8781cc75a5a81cab84c748b53737d906f95c8d10337d365fd88cb3bbdd938517' 
  AND token = '0d1MEwSjZsWfWO4HnCivzKaLqAkbPMLmH4DwQgtJUZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}