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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1101057306ec4fec25b2a50225f41ba068bb27cd5a682240f5c9d7c92be43a4d' 
  AND token = 'NQW9vkmTuK3AFUlWq0U7xDX+fbsufvMqE7BpH5QyMs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}