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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c3d3b8db50682eeb80710c6aa8d46cd8626c0a8a02e2f5f2bce5ecfa220ff9' 
  AND token = 'HnZDMyvI55e+1SBi4iB6zyx+qnUR3GI9yCq/jGHgK9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}