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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33f22945b6f45ed4fb4eb30ca08940815c98ca1d37bfc4aecf4a64a19a0a7166' 
  AND token = 'qlelvsvijN/E4aiN6XClmCTRV1W7/Q9qdL7JP3uEBMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}