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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd50382a5e83242cac719e0ae26c0f91a09136dd4fbeeeb2a519274456be5a2d7' 
  AND token = 'QAID+uG3k72at33MSx1UioK6NmxGrjcCttWcmVXtsMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}