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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2073c5e5c4405befff0339fdd17537309bad2b2925c91b0dda43a373a684234f' 
  AND token = 'Ml5JCaiN2bBfnQj3HGINAhKJHK2GBpLlTTDPI8Gqx38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}