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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed446d308a44db5bc2fa0a64f2fe0711e2355bbd98dd439cd334705c7554bc1' 
  AND token = 'N9Yrs9NcxgI6eW0HpyFGL+QtFL6ac+rSXLRIjpMt9HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}