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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5127be600c119e6cf5c305a1047f129e60a3f1ab95eda4434e584944e8286a' 
  AND token = 'm2JMRvXvfFvbTrquDeVouaAF/LizpK6npZ6nkHS4/Fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}