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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca7293812b3637b205f84b0a1830014fa36573fd8e9b3a1750e860eec696be6b' 
  AND token = 'wGpoCaRxoFq3fg52vztS8jI86u1ANl1kRt+OdPTV9nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}