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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f591b9b02f0c1c2540e9354a1e962845104b509acfb3f91f0957690beac08e9d' 
  AND token = 'v5tQiAWr65P07yc65A5LO0LUSodtWCmOI/RgDdq3gA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}